About the Goyal Lab
The Goyal Lab investigates cell signaling and molecular medicine, with particular emphasis on poorly characterized protein kinases and disease-relevant signaling networks. Our research integrates molecular and cellular biology with structural, computational, and disease-oriented approaches to understand how signaling proteins regulate cellular behavior and contribute to human disease. Current areas include STK35/STK35L1, PDIK1L and EGFR/HER2-associated signaling, cofilin biology and protein aggregation, PAI-1 signaling, host–pathogen interactions, and related questions in molecular medicine.
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Our research has evolved from the molecular identification and characterization of signaling proteins toward increasingly integrated questions in cell biology and disease. Studies of STK35/STK35L1 progressed from kinase identity and evolutionary relationships to nuclear actin, cell-cycle regulation, cell migration, host–pathogen interactions, structural regulation, and cancer biology. This progression now provides the foundation for broader investigations into kinase signaling, disease mechanisms, and molecular medicine.
Latest Event
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Invited Talk: Deciphering the Multifaceted Roles of the STK35 Family
September 12, 2026
50+
PEER-REVIEWED PUBLICATIONS
20+
YEARS IN MOLECULAR MEDICINE RESEARCH
15+
YEARS OF PG & PhD TEACHING / SUPERVISION
Selected Publications & Research Output
The Goyal Lab has published across protein kinase biology, cell signaling, cancer biology, host–pathogen interactions, cytoskeletal regulation, and molecular medicine. Recent work extends our long-standing STK35/STK35L1 program into breast cancer and disease signaling.
- Identification of STK35L1 as a potential prognostic biomarker in breast carcinoma, and its expression exhibits high correlation with EGFR activity. Functional & Integrative Genomics (2026).
- Differential Expression of STK35L1-Associated Transcription Factors in Plasmodium Infection During the Liver Stage of Malaria. Kinases and Phosphatases (2025).
- STK35L1 regulates Plasmodium infection and expression of cell cycle genes during the liver stage of malaria. Experimental Cell Research (2021).
